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Human TNFRSF10A protein

SKU
Name
Human TNFRSF10A protein
Size
50 ug
Price
$398.00
Qty

Human TNFRSF10A protein

Description
Recombinant protein from the full-length sequence of Homo sapiens TNF receptor superfamily member 10a (TNFRSF10A) (NM_003844), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_003844; NP_003835; UniProt#: O00220; GeneID: 8797;
Synonyms
APO2; CD261; DR4; TRAILR-1; TRAILR1
Molecular Weight
50.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]

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