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Human CYP2C8 protein

SKU
Name
Human CYP2C8 protein
Size
50 ug
Price
$398.00
Qty

Human CYP2C8 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens cytochrome P450 family 2 subfamily C member 8 (CYP2C8), transcript variant 1 (NM_000770), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_000770; NP_000761; UniProt#: P10632; GeneID: 1558;
Synonyms
CPC8; CYPIIC8; MP-12/MP-20
Molecular Weight
55.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mePHXXXXXXN, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].

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