Human ADARB1 protein

Description

Recombinant protein from the full-length sequence of Homo sapiens adenosine deaminase, RNA specific B1 (ADARB1), transcript variant 2 (NM_015833), with a DYKDDDDK tag.

Host

Human Cells

Tags

DYKDDDDK

RefSeq Link

NM_015833; NP_056648; UniProt#: P78563; GeneID: 104;

Synonyms

ADAR2; DRABA2; DRADA2; RED1

Molecular Weight

80.6 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]