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Human CYP11A1 protein

SKU
Name
Human CYP11A1 protein
Size
50 ug
Price
$398.00
Qty

Human CYP11A1 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens cytochrome P450 family 11 subfamily A member 1 (CYP11A1), transcript variant 2 (NM_001099773), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_001099773; NP_001093243; UniProt#: P05108; GeneID: 1583;
Synonyms
CYP11A; CYPXIA1; P450SCC
Molecular Weight
42 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008].

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