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Human ADARB1 protein

SKU
Name
Human ADARB1 protein
Size
50 ug
Price
$398.00
Qty

Human ADARB1 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens adenosine deaminase RNA specific B1 (ADARB1), transcript variant 1 (NM_001112), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_001112; NP_001103; UniProt#: Q86W11; GeneID: 104;
Synonyms
ADAR2; DRABA2; DRADA2; RED1
Molecular Weight
76.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]

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