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Human TSHR protein

SKU
Name
Human TSHR protein
Size
50 ug
Price
$398.00
Qty

Human TSHR protein

Description
Recombinant protein from the full-length sequence of homo sapiens thyroid stimulating hormone receptor (TSHR), transcript variant 1 (NM_000369), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_000369; NP_000360; UniProt#: P16473; GeneID: 7253;
Synonyms
CHNG1; hTSHR-I; LGR3
Molecular Weight
84.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].

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