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Human AXL Protein

SKU
Name
Human AXL Protein
Size
50 ug
Price
$398.00
Qty

Human AXL Protein

Description
Recombinant protein of the extracellular domain (Ala26-Trp451) of homo sapiens AXL receptor tyrosine kinase (AXL), transcript variant 1 (NM_021913), with a polyhistidine tag;
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_021913; NP_068713; UniProt#: P30530; GeneID: 558;
Synonyms
ARK; JTK11; Tyro7; UFO
Molecular Weight
50 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

SDS-Page Image
Fig 1 : SDS-Page Image
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