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Human FCAR protein

SKU
Name
Human FCAR protein
Size
50 ug
Price
$398.00
Qty

Human FCAR protein

Description
Recombinant protein from the full-length sequence of homo sapiens Fc fragment of IgA receptor (FCAR), transcript variant 1 (NM_002000), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_002000; NP_001991; UniProt#: P24071; GeneID: 2204;
Synonyms
CD89; CTB-61M7.2; FcalphaRI
Molecular Weight
32.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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