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Human TNFSF10 protein

SKU
Name
Human TNFSF10 protein
Size
50 ug
Price
$398.00
Qty

Human TNFSF10 protein

Description
Recombinant protein from the full-length sequence of homo sapiens tumor necrosis factor superfamily member 10 (TNFSF10), transcript variant 1 (NM_003810), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_003810; NP_003801; UniProt#: P50591; GeneID: 8743;
Synonyms
Apo-2L; APO2L; CD253; TL2; TRAIL
Molecular Weight
32.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. [UniProtKB/Swiss-Prot Function]

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