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Human CYP27A1 protein

SKU
Name
Human CYP27A1 protein
Size
50 ug
Price
$398.00
Qty

Human CYP27A1 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens cytochrome P450 family 27 subfamily A member 1 (CYP27A1) (NM_000784), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_000784; NP_000775; UniProt#: Q02318; GeneID: 1593;
Synonyms
CP27; CTX; CYP27
Molecular Weight
60.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008].

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