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Human CYP51A1 protein

SKU
Name
Human CYP51A1 protein
Size
50 ug
Price
$398.00
Qty

Human CYP51A1 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens cytochrome P450 family 51 subfamily A member 1 (CYP51A1), transcript variant 1 (NM_000786), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_000786; NP_000777; UniProt#: Q16850; GeneID: 1595;
Synonyms
CP51; CYP51; CYPL1; LDM; P450-14DM; P450L1
Molecular Weight
57.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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