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Human TNFRSF4 protein

SKU
Name
Human TNFRSF4 protein
Size
50 ug
Price
$398.00
Qty

Human TNFRSF4 protein

Description
Recombinant protein from the full-length sequence of homo sapiens tumor necrosis factor receptor superfamily member 4 (TNFRSF4) (NM_003327), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_003327; NP_003318; UniProt#: P43489; GeneID: 7293;
Synonyms
ACT35; CD134; IMD16; OX40; TXGP1L
Molecular Weight
29.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

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