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Human TNFRSF10B protein

SKU
Name
Human TNFRSF10B protein
Size
50 ug
Price
$398.00
Qty

Human TNFRSF10B protein

Description
Recombinant protein from the full-length sequence of Homo sapiens TNF receptor superfamily member 10b (TNFRSF10B), transcript variant 2 (NM_147187), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_147187; NP_671716; UniProt#: O14763; GeneID: 8795;
Synonyms
CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
Molecular Weight
45.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

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