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Human PPP1R1A protein

SKU
Name
Human PPP1R1A protein
Size
50 ug
Price
$398.00
Qty

Human PPP1R1A protein

Description
Recombinant protein from the full-length sequence of Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 1A (PPP1R1A) (NM_006741), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_006741; NP_006732; UniProt#: Q13522; GeneID: 5502;
Synonyms
I1; IPP1
Molecular Weight
18.8 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. [UniProtKB/Swiss-Prot Function]

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