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Recombinant Human TMPRSS2 Protein

SKU
Name
Recombinant Human TMPRSS2 Protein
Size
50 ug
Price
$398.00
Qty

Recombinant Human TMPRSS2 Protein

Description
Recombinant protein of the extracellular domain (M109-G492) of human transmembrane protease serine 2 (TMPRSS2), with an c-terminal polyhistidine tag.
Host
Human cells
Tags
His
RefSeq Link
NM_005656; NP_005647; UniProt#: O15393; GeneID: 7113;
Synonyms
TMPS2; PRSS10
Molecular Weight
49 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

SDS-Page Image
Fig 1 : SDS-Page Image
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