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OX-2 membrane glycoprotein (CD200/MOX1)

External ID
UniProt:
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EUPROTEIN has developed and validated CD200/OX-2 membrane glycoprotein that could be potentially used in the anti-cancer drug discovery. Sale: Just $99 for 100ug

Human OX-2 protein from Expi293 cell
Fig 1. Human OX-2 membrane glycoprotein (EPW128118) from Human Expi293 cells.
Human OX-2 protein IgG1 Fc tag
Fig 2. Human OX-2 membrane glycoprotein (EPY98701) with a Human IgG1 Fc tag.

Background

CD200, also known as OX-2 membrane glycoprotein, is a type-1 membrane glycoprotein, which contains two immunoglobulin domains and thus belongs to the immunoglobulin superfamily. This protein costimulates T-cell proliferation and may regulate myeloid cell activity in a variety of tissues. CD200 is also believed to regulate immune responses by negative regulation of macrophage activation.

Implication of CD200/OX-2 in Cancer Immunology

CD200 is shown to suppress the immune system’s responses to cancer in mainly three ways:

To neutralize the immune suppression by CD200, scientists have been working on applying inhibitory peptide to activate the immune system through a CD200 activation receptor. Alternatively, anti-CD200 receptor antibodies could allow tumor-killing cells to pass through the blood vessel walls, enabling natural killing activities.

EUPROTEIN Offering

EUPROTEIN has developed and validated CD200/OX-2 membrane glycoprotein that could be potentially used in the anti-cancer drug discovery. This high-quality protein might also be applied in future development of diagnostic assays for tumors or therapies involved CD200/OX-2.

Human OX-2 protein from Expi293 cell
Fig 1. Human OX-2 Membrane Glycoprotein from Human Expi293 cells
Human OX-2 protein IgG1 Fc tag.jpg
Fig 2. Human OX-2 Membrane Glycoprotein with a Human IgG1 Fc tag

These proteins are on sale right now, only $99 for 100ug! Place order now.

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